Group B had higher IgA, IgG, and IgM levels, higher CD4 +, CD3 + levels and lower CD8 + levels as well as higher IGF-1, 25-(OH)D 3, INF-y levels, and fewer respiratory infections after treatment than group A ( P<0.05). Children in group B had shorter time to disappearance of lung rales, cough, and fever than group A ( P<0.05). Results: The total effective rate of treatment in group B was 96.67%, which was significantly higher than 71.19% in group A ( P<0.05).

The clinical efficacy, symptom disappearance time, immune function index, insulin-like growth factor (IGF-1), 25-hydroxyvitamin D 3, serum y-interferon (INF-y), and the number of episodes of respiratory tract infections were compared between the two groups. Methods: The clinical data of 119 children with RRTI in our hospital were retrospectively retrieved, and they were divided into group A (n=59, receiving routine treatment) and group B (n=60, receiving vitamin D drops) based on their treatment modality. Objective: To investigate the effects of vitamin D drops on immune function in children with recurrent respiratory tract infections (RRTI).

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